Advances in Brain Imaging/Morihisa JM (editor): Advances in Brain Imaging (Review of Psychiatry Series, Volume 20, Number 4; Oldham JM and Riba MB, series editors). Washington,DC, American Psychiatric Publishing, 2001

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Contents:
Contributors ix
Introduction to the Review of Psychiatry Series xi
John M. Oldham, M.D., and
Michelle B. Riba, M.D., M.S., Series Editors
Foreword xv
John M. Morihisa, M.D.
Chapter 1
Functional Brain Imaging in
Psychiatry: The Next Wave 1
Joseph H. Callicott, M.D.
Functional Magnetic Resonance
Imaging (fMRI) in Psychiatry 3
A Dynamic Approach to Brain
Mapping in Psychiatry 8
Magnetic Resonance and Genetic Susceptibility 15
Conclusions 17
References 18
Chapter 2
Cognitive Neuroscience: The New
Neuroscience of the Mind and
Its Implications for Psychiatry 25
Cameron S. Carter, M.D.
Executive Functions and the Brain 27
ACC and Performance Monitoring 29
DLPFC and Top-Down Control 32
Impaired Executive Functions in
Schizophrenia: Role of DLPFC and ACC 36
DLPFC and Impaired Executive
Functions in Schizophrenia 38
ACC and Impaired Performance
Monitoring in Schizophrenia 41
Overcontrol and Dysfunctional Performance
Monitoring in OCD: Role of the ACC 43
Conclusions 45
References 47
Chapter 3
Functional Magnetic Resonance Imaging in
Children and Adolescents: Implications for
Research on Emotion 53
Daniel S. Pine, M.D.
Developmental Psychopathology Perspectives
Applied to Mood and Anxiety Disorders 55
Data Implicating Neural Circuits in
Pediatric Mood and Anxiety Disorders 59
Using fMRI to Probe Developmental
Dysfunction in Neural Circuits 66
Conclusions 74
References 75
Chapter 4
Brain Structure and Function in
Late-Life Depression 83
Harold A. Sackeim, Ph.D.
Brain Structural Abnormalities: Encephalomalacia 84
Etiology of Encephalomalacia 91
Pathophysiology of Encephalomalacia 94
Volumetric Brain Structural Abnormalities 97
Functional Brain Abnormalities 105
Treatment and Recovery Effects in
Late-Life Depression 110
Conclusions 113
References 115
Chapter 5
Neuroimaging Studies of Major Depression 123
Wayne C. Drevets, M.D.
Overview of the Imaging Research Program 124
Neurophysiological Imaging
Studies of Major Depression 127
Functional Anatomical Correlates of Depression 138
Anatomic Circuits Implicated in MDD 153
Histopathological Findings in the
L-T-C and L-C-S-P-T Circuits 154
Clinical Implications and
Directions for Future Studies 158
References 159
Afterword 171
John M. Morihisa, M.D.
Index 175

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